I have developed a tool for VST2 synthesizers for finding new sounds from synths. (Novel Insight Hypercube VST)
The freeware machine learning tool maps synthesizer parameters to just three parameters which can explored more easily. (The software requires that there are large number presets which are used to calculate parameter reduction (not all VST2 synths allow reading of preset values))
Here is sourceforge site of the tool (Installer and example video):
Tomas Ukkonen, M. Sc.